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tecovirimat will boost the stage or effect of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Tecovirimat is a weak inhibitor of CYP2C8 and CYP2C19. Keep track of for adverse results if coadministered with delicate substrates of those enzymes.iloperidone improves levels of modafinil by affecting hepatic/intest